Maternal Age: Region

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Cases with more than one anomaly within a group are counted only once. Numbers reflect cases where that anomaly occurs in a baby of a mother who falls into that age range. The maternal age is taken as being that at the end of the pregnancy.

Maternal Age: Region	< 20	20 - 24	25 - 29	30 - 34	35 - 39	40 - 44	> 44	Not Known	Total
A: Neurological	50	124	133	168	99	17		8	599
All neural tube defects	28	44	58	72	46	8		1	257
anencephalus	12	21	25	29	21	2			110
spina bifida	13	17	29	33	22	5		1	120
encephalocele	4	6	5	11	6	1			33
Congenital hydrocephalus	5	31	22	52	19	3		1	133
Muscular dystrophy				3					3
Duchenne MD				1					1
B: Eye Ear Face Neck	23	52	75	90	76	16	1	4	337
All eye	16	22	34	35	32	5		4	148
anopthalmos / micropthalmos	2	4	6	4	7	1			24
congenital cataract	3	4	5	7	4	1		2	26
anomalies surrounding structures	1	3	5	8	2	2		1	22
All ear	2	8	7	18	10	1			46
external ear anomalies		2	2	3	6				13
sensorineural hearing loss	1	3	1	3					8
C: Circulatory	97	206	280	326	212	62	9	17	1209
Disordered circulation	6	8	8	10	9	3			44
All septal defects	61	122	157	203	133	45	6	11	738
ASD (all types)	20	36	49	58	42	12	2		219
VSD	44	91	115	146	92	31	3	9	531
AVSD	7	10	13	21	18	10	2	2	83
All complex cyanotic CHD	10	13	26	29	17	2		2	99
transposition great vessels	7	6	18	20	9				60
tetralogy of Fallot	3	7	8	9	8	2		2	39
All heart valve anomalies	28	31	41	67	31	11	3	4	216
pulmonary valve anomalies	14	15	14	24	15	4	2	2	90
tricuspid valve anomalies	5	9	12	11	6	2			45
mitral valve anomalies	3	2	3	9	1	1	1		20
aortic valve anomalies	8	6	14	26	8	4	2	2	70
All vessel anomalies	32	63	80	87	59	16	2	3	342
pulmonary artery anomalies	15	24	32	35	21	7			134
aorta anomalies	15	27	42	41	29	7	2	1	164
All chamber anomalies	22	40	58	71	33	12	3		239
hypoplastic left heart	2	15	21	20	6	4	1		69
hypoplastic right heart			1	1					2
Conduction anomalies	3	10	8	10	8	1			40
D: Respiratory	20	46	68	48	42	9	1	1	235
All airways	14	28	43	33	28	5	1		152
All lung	9	22	31	20	15	5		1	103
cystic anomalies	2	6	7	4	4	2		1	26
agenesis	2	5	9	7	3	1			27
hypoplasia	6	5	7	9	4	2			33
E: Digestive	52	148	202	208	119	29	3	10	771
All clefting	25	65	88	85	47	17	2	4	333
lips	6	17	19	19	14	2			77
alveolar	1	1	3	2	1	1			9
isolated cleft palate	10	16	38	38	15	10	2	3	132
cleft palate with cleft lip	9	32	30	28	18	5		1	123
All oesophagus / stomach	3	19	16	23	10	2			73
tracheo-oesophageal atresia, fistula, stenosis	3	15	14	20	9	2			63
All intestines	17	50	68	65	49	7	1	5	262
duodenal atresia	1	6	5	8	8			1	29
other small bowel atresias	1	4	4	7	5	1			22
large bowel atresias	6	20	22	13	16	3		1	81
Hirschsprung's disease	1	7	7	10	3	1			29
All digestive organs	3	15	21	18	11	1			69
bilary atresia		1	4	1	2				8
F: Urinary	44	109	196	217	114	30	2	6	718
All kidney	28	70	115	115	65	17	1	2	413
agenesis	6	10	18	28	16	4			82
hypoplasia	2	3	10	7	5	1			28
cystic	9	30	45	28	25	7		1	145
other specific kidney	8	16	28	40	19	4	1	1	117
All renal pelvis / ureters	18	45	89	112	52	12	1	2	331
pelviureteric obstruction	10	34	64	83	37	7	1	2	238
hydronephrosis, 10mm or over	9	14	26	37	22	2			110
All bladder / urethra	8	16	32	34	12	6		1	109
epispadias		1		3	1	1			6
G: Genital	49	133	204	229	130	25	2	7	779
Female	7	8	16	25	16	3			75
Male	42	123	182	202	112	22	2	6	691
hypospadias	32	83	125	144	80	16	2	6	488
Intersex		2	7	3	2	1		1	16
H: Endocrine, metabolic	11	30	40	41	27	10	1	4	164
All thyroid	3	2	6	3	6				20
hypothyroidism	3	2	6	3	6				20
Phenylketonuria
Cystic fibrosis	3	4	8	9	4	4		3	35
Adrenal	1	6	9	11	4	2			33
J: Blood, immune, lymphatic	5	12	16	23	12	1			69
Thalassaemia		2	2	4					8
Sickle cell	1	1	3	2	1	1			9
Immunodeficiency	1								1
K: Skin	9	34	48	60	38	9		5	203
Cystic hygroma	4	15	26	33	29	8		4	119
L: Limbs	93	224	353	401	208	62	2	10	1353
All upper limb	31	90	113	131	79	18		5	467
polydactyly	10	35	34	44	24	6		2	155
syndactyly	5	7	14	15	6	2		2	51
reduction defects	9	33	44	50	31	4		2	173
All lower limb	58	147	257	286	143	45	2	7	945
polydactyly	3	10	16	22	6	3	1		61
syndactyly	3	26	27	35	12	7			110
reduction defects	9	19	36	30	17	3		1	115
dysplastic hip	9	27	51	57	37	11		5	197
non-postural talipes	20	39	68	69	29	15		1	241
Non limb-specific	16	21	28	40	23	5			133
M: Musculoskeletal	81	117	162	181	119	20	1	7	688
All abdominal wall defects	37	45	39	27	26	5		2	181
gastroschisis	27	26	10	3	2	1			69
exomphalos	8	14	23	21	22	4		2	94
All diaphragm	4	16	18	26	13			1	78
hernia / agenesis	4	16	17	24	12			1	74
All short stature	1	3	4	11	8	1	1	1	30
achondroplasia	1		1	6	3			1	12
All other specific musculoskeletal	41	65	115	123	89	14		3	450
skull, face & neck	20	21	63	61	47	12		3	227
thorax & trunk	9	9	29	20	18	2			87
spine & pelvis	14	23	25	29	28	1			120
N: Neoplastic	2	3	2	8	4	1			20
O: Genetic / multi-site disorders	42	106	187	290	350	226	17	16	1234
All chromosomal	34	93	167	272	339	221	17	16	1159
trisomy 21 - Down's syndrome	9	26	50	112	178	124	6	7	512
trisomy 18 - Edwards' syndrome	4	10	25	27	49	38	5	3	161
trisomy 13 - Patau's syndrome	1	6	6	18	17	5	1		54
triploidy / polyploidy	3	4	15	17	7	3		1	50
Turner's syndrome	3	10	14	23	13	6		2	71
Klinefelter's syndrome	1	3	2	2	5	5	2		20
other anomalies sex chromosomes		3	3	5	8	8			27
deletions	7	16	24	23	16	6		2	94
other chromosome anomalies	6	16	30	46	46	30	3	1	178
Other genetic disorder	7	14	20	18	15	5			79
P: Pregnancy related	8	19	23	30	14	3			97
R: Infectious	11	2	12	16	16	2			59
viral	5		3	5	4				17
bacterial			3						3
fungal
S: Suggestion of underlying anomaly	12	18	31	44	40	8		1	154
hydrops	6	14	21	26	27	5			99

Additional anomalies collected by SWCAR For our own purposes SWCAR have decided to continue collection of the following anomalies on the EUROCAT exclusion list; they are not included in the overall data numbers/rates above.
pyloric stenosis	23	37	51	40	13	4		12	180
inguinal hernia	27	69	83	124	61	10		12	386
balanced translocation	1		4	8	3	1			17
café au lait spot				1	1	1			3
other branchial cleft malformations					1				1
hydronephrosis >=5mm <10mm	13	50	63	80	36	11		1	254
vesicoureteric reflux	3	9	15	13	8	3			51
congenital subluxation of hip	3	5	8	12	9	1			38